Clinical Chemistry Controls
Med Vet International petMAP Mobile Veterinary Monitoring Accessories - ECG Lead Wire Set (Snap), J1750J, Each
petMAP Mobile Veterinary Monitoring Accessories - ECG Lead Wire Set (Snap), J1750J, Each
Biotium Catenin, gamma (Cardiomyocyte Marker)(CTNG/2155R), CF647 conjugate, 0.1mg/mL
Gamma catenin, also known as JUP or junction plakoglobin, is a member of the catenin family. The catenins (alpha, beta, gamma, and delta) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion, including adherens junctions. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Catenin, gamma (Cardiomyocyte Marker)(CTNG/2155R), CF740 conjugate, 0.1mg/mL
Gamma catenin, also known as JUP or junction plakoglobin, is a member of the catenin family. The catenins (alpha, beta, gamma, and delta) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion, including adherens junctions. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
AURORA BIOLABS LLC PD-1/PD-L1 Inhibitor Binding Assay Kit,384 rxn
Immune checkpoint blockade is an important cancer immunotherapy strategy that enhances the immune system’s ability to recognize and destroy tumor cells. The PD-1/PD-L1 signaling pathway is a key immune checkpoint that suppresses T-cell activity and allows cancer cells to evade immune surveillance. Blocking the interaction between PD-1 and PD-L1 can restore immune function and improve anti-tumor responses. The PD-1/PD-L1 Inhibitor Binding Assay is a TR-FRET–based assay designed to quantitatively measure the interaction between PD-1 and PD-L1. In this assay, binding of PD-1 to PD-L1 generates a fluorescence resonance energy transfer (FRET) signal that can be detected by measuring fluorescence emission at 665 nm and 620 nm. Compounds or antibodies that inhibit PD-1/PD-L1 binding reduce the TR-FRET signal, enabling evaluation of potential immune checkpoint inhibitors for cancer research and drug discovery applications.